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(AsiaGameHub) –   The March Madness Final Four is now set following UConn’s remarkable comeback victory against Duke on Sunday. Saturday’s matchups will feature No. 3 Illinois facing No. 2 UConn (6:09 ET, TBS) and No. 1 Michigan against No. 1 Arizona (8:49 ET, TBS).

Here is a look back at yesterday’s incredible buzzer-beater by Braylon Mullins:

BRAYLON MULLINS. THE SHOT. https://t.co/0V6OnPolR2 pic.twitter.com/5B83KGMdVT

— UConn Men’s Basketball (@UConnMBB) March 29, 2026

Let’s now review the Final Four odds before we present our predictions and picks.

Final Four Odds at DraftKings Sportsbook

As of publication, DraftKings has Illinois listed as a 2.5-point favorite over UConn, with a total of 139.5. Michigan is a 1.5-point favorite against Arizona, with a total of 157.5.

Below are the championship futures odds for each of the remaining teams:

• Michigan +175
• Arizona +175
• Illinois +400
• UConn +550

Best Bet Illinois vs. UConn: Against the Spread

UConn managed to overcome a 19-point deficit to defeat Duke in the Elite Eight. The Huskies, with a record of 33-5, are led by center Tarris Reed Jr. (averaging 14.7 points and 8.8 rebounds) and forward Alex Karaban (averaging 13.2 points and 5.2 rebounds).

Duke’s defense effectively contained Karaban in their last game, limiting him to just five points. Reed stepped up to lead the team with 26 points. However, the roles might be reversed for UConn against Illinois, whose strong interior defense held Iowa to only seven two-point field goals.

Illinois’ offense is spearheaded by freshman sensation Keaton Wagler, who contributed 25 points in the Illini’s 71-59 victory over Iowa. David Mirkovic, a crucial player in the Illini’s frontcourt, has been dominant on the boards throughout the NCAA Tournament.

Here are his rebounding statistics from all four tournament games:

• Penn (17)
• VCU (5)
• Houston (10)
• Iowa (12)

Mirkovic is averaging 11 rebounds per game during March Madness.

UConn commits an average of 18 fouls per game, ranking 225th nationally. If this trend continues and Illinois’ interior defense maintains its effectiveness, we favor the favorite to win and cover in the first semifinal.

Pick: Illinois -2.5 (-102 at DraftKings)

Best Bet Michigan vs. Arizona: UNDER 157.5

Michigan has surpassed 90 points in all four of their tournament games. Arizona, while not as consistently high-scoring, did manage to score 109 points against Arkansas in the Sweet Sixteen. How could this game stay under the total?

Arizona secured a lower-scoring victory in the Elite Eight, defeating Purdue 79-64. It’s worth noting that Purdue had previously beaten Michigan in the Big Ten championship game before the start of March Madness.

The Wildcats primarily score their points in the paint, but Michigan presents a significant challenge with their 7-foot-3 center, Aday Mara, leading the rim protection. KenPom ranks the Wolverines as the No. 1 team in adjusted defensive efficiency. Concurrently, Arizona limits opponents to just 39% shooting from the field.

We are taking the UNDER on this high total.

Pick: UNDER 157.5 (-110)

Best Player Props for Final Four

UConn’s Alex Karaban OVER 11.5 Points (-122 at FanDuel)

As previously mentioned, Duke’s defense stifled Karaban, but he scored 22, 27, and 17 points in the first three tournament games.

While Illinois’ defensive strength is primarily inside, Karaban often scores from beyond the three-point arc. Iowa managed to shoot 37% from three-point range and made 11 treys against Illinois.

Karaban, who leads the Huskies with 73 three-pointers this season, shoots 38.6% from long range. This matchup appears favorable for a strong performance from the senior forward.

Michigan’s Yaxel Lendeborg OVER 16.5 Points (-114 at FanDuel)

Yaxel Lendeborg is having a tournament performance that could warrant consideration for Most Outstanding Player. Lendeborg’s last three games have been exceptionally efficient:

• 27 points, seven rebounds vs. Tennessee
• 23 points, 12 rebounds vs. Alabama
• 25 points, 6 rebounds vs. St. Louis

Additionally, consider betting on him to make OVER 2.5 three-pointers at +200 odds. Lendeborg has made three, four, and three three-pointers in his last three games, respectively.